306 research outputs found

    The Indian elections : a diary

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    "June 1977.""2135"--handwritten on cove

    Seeking ethnic equality : a case study of migration and employment policies in an Indian state

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    "September 1977.""2146"--handwritten on coverIncludes bibliographical reference

    Congress restored, political and economic developments in contemporary India

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    "August 1981."Prepared for the fourth Joint Soviet-American Conference on Asia, Tashkent, September 1981"#2340"--handwritten on cove

    American political affiliation, 2003–43: a cohort component projection

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    The recent rise and stability in American party identification has focused interest on the long-term dynamics of party bases. Liberal commentators cite immigration and youth as forces which will produce a natural Democratic advantage in the future while conservative writers highlight the importance of high Republican fertility in securing Republican growth. These concerns foreground the neglect of demography within political science. This paper addresses this omission by conducting the first ever cohort component projection of American partisan populations to 2043 based on survey and census data. A number of scenarios are modeled, but, on current trends, we predict that American partisanship will shift much less than the nation’s ethnic composition because the parties’ age structures are similar. Still, our projections find that the Democrats gain two to three percentage points from the Republicans by 2043, mainly through immigration, though Republican fertility may redress the balance in the very long term

    Cerebral blood volume in Alzheimer's disease and correlation with tissue structural integrity

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    A vascular component is increasingly recognized as important in Alzheimer's disease (AD). We measured cerebral blood volume (CBV) in patients with probable AD or Mild Cognitive Impairment (MCI) and in elderly non-demented subjects using a recently developed Vascular-Space-Occupancy (VASO) MRI technique. While both gray and white matters were examined, significant CBV deficit regions were primarily located in white matter, specifically in frontal and parietal lobes, in which CBV was reduced by 20% in the AD/MCI group. The regions with CBV deficit also showed reduced tissue structural integrity as indicated by increased apparent diffusion coefficients, whereas in regions without CBV deficits no such correlation was found. Subjects with lower CBV tended to have more white matter lesions in FLAIR MRI images and showed slower psychomotor speed. These data suggest that the vascular contribution in AD is primarily localized to frontal/parietal white matter and is associated with brain tissue integrity

    MANUSCRIPT IN PRESS: DEMENTIA & GERIATRIC COGNITIVE DISORDERS: Molecular Neuropsychology: Creation of Test-Specific Blood Biomarker Algorithms

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    Prior work on the link between blood-based biomarkers and cognitive status has largely been based on dichotomous classifications rather than detailed neuropsychological functioning. The current project was designed to create serum-based biomarker algorithms that predict neuropsychological test performance
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